Platelet Concentrate (for face)

What is Platelet Concentrate   

 The platelet concentrate prepared with this RegenLab technology provides an autologous reservoir of growth factors.

Platelets are key factors in tissue repair mechanisms. They provide essential growth factors, such as FGF, PDGF, TGF-β, EGF, VEGF, IGF, which are involved in stem cell migration, differentiation and proliferation. Platelets also stimulate fibroblasts and endothelial cells to induce the deposition of new extracellular matrix and neovascularization, respectively. The platelets are concentrated from the patient’s own blood.

Plasma contains many factors essential for cell survival including nutrients, vitamins, hormones, electrolytes, growth factors (such as IGF and HGF), and proteins. Among the plasma proteins, the molecules vital for the coagulation process and fibrin polymer formation will serve as a scaffold for cell migration and new tissue generation.

The platelet concentrate could be considered as

 an effective procedure for facial

 rejuvenation as it induces collagen

 production in the dermis.

RegenLab® is a leading innovator of medical products for the preparation of platelet rich plasma.

Regen Lab provides expertly designed & patented Medical Devices for platelet-rich plasma preparations, CE certified, registered by most national agencies worldwide.

Regen Lab remains committed to providing products of the highest quality and safety.

TECHNOLOGY PLATFORM FOR STANDARDISED

 AUTOLOGOUS REGENERATIVE MEDICINE

The simple, safe and efficient point of care preparation of autologous platelet-rich plasma

BIOLOGICAL ADVANTAGES

• Platelet recovery > 80%  

• High platelet quality.

Viable & functional platelets

• Full plasma recovery.

No loss of plasma growth factors and fibrinogen

• Leucocyte reduced platelet concentrate

Depletion of 96.7% of pro-inflammatory granulocytes,

leaving mainly lymphocytes and monocytes

• Virtually no red blood cells.

Depletion of ~ 99.7% of erythrocytes 

CLINICAL EVIDENCE

NEW COLLAGEN

Histologic evidence of new collagen formulation using platelet rich plasma in skin rejuvenation

In this prospective controlled clinical study, the authors evaluated the efficacy of an intradermal injection of platelet concentrate for humanfacial rejuvenation (20 patients) by performing histological examinations before and after treatment and measuring the mean opticaldensities (MODs) of collagen.

       · The authors observed that the MOD of collagen fibers was clearly higher on the platelet concentrate side compared to the saline injected side (p < 0.001). These data are in line with previous in vivo work showing the effect of The platelet concentrate on the rejuvenation of photoaged skin in nude mice4. 

· The authors observed no serious side effects following The platelet concentrate treatment.

SKIN REVITALISATION

Face and neck revitalization with platelet-rich plasma

In this case series of 23 patients, the authors evaluated if there are real outcomes, benefits, and side effects following a standardized platelet concentrate injection protocol DGS was calculated by comparing the spider improvement score, the pre-and post-improvement photographs, the patient’s satisfaction score, and the doctor’s satisfaction score.. Patients received a platelet concentrate injection once a month for three months. Patients were evaluated one month after the last injection. A definitive graduated score (DGS) was calculated for each patient.

• The authors concluded that face and neck revitalisation withplatelet concentrate is a promising, easy-to-use technique, performing favorably in all small skin wrinkles, as well as in skin texture and elasticity assessments.

ACNE SCARS